Additional information
| Active substance | Tolvaptan | 
|---|---|
| Water Retention | Reduces water retention by promoting free water excretion | 
| Hepatotoxicity | Can cause significant increases in liver enzymes, potential for serious liver injury | 
| Lab Test | Monitoring of serum sodium levels and liver function tests are necessary | 
| Strength | 30mg | 
| Also known as | OPC-41061 | 
| Blood pressure | Generally has minimal effect on blood pressure | 
| Trade name | Samsca | 
| Storage conditions | Store at room temperature away from moisture and heat | 
| Chemical name | N-[4-[(5R)-7-chloro-5-hydroxy-2-oxo-3-oxabicyclo[4.3.0]nona-1,6-dien-9-yl]pentyl]-1-methylbenzimidazole-2-carboxamide | 
| Formula | C_26H_25ClN_2O_3 | 
| Substance class | Benzazepine derivative | 
| Main action | Vasopressin V2 receptor antagonist | 
| Half-life | Approximately 12 hours | 
| Dosage (medical) | Initial dose of 15 mg once daily, may be increased to a maximum of 60 mg daily based on serum sodium levels and clinical response | 
| Dosage (sports) | Not applicable as it is not typically used in sports | 
| Effects | Increases urine output without affecting the excretion of potassium and sodium, corrects hyponatremia | 
| Side effects | Thirst, dry mouth, nausea, polyuria, hyperglycemia, raised liver enzymes | 
| Use in sports | None, as it is not known to enhance athletic performance | 
| Manufacturer | Centaur Pharmaceuticals Pvt. Ltd | 
| Packing | 4 tabs/blister | 
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